Introduction The USMLE Step 3 marks the culmination of the United States Medical Licensing Examination (USMLE) series, serving as the final assessment in the sequence. This comprehensive exam spans two days and evaluates a candidate's ability to apply medical knowledge and understand biological and clinical science concepts essential for the independent practice of medicine, with a particular focus on patient management in ambulatory settings. When to Take USMLE Step 3 Step 3 is typically undertaken upon completion of medical school and residency training, as it is a prerequisite for obtaining an unrestricted medical license in the United States. The Step 3 exam comprises two parts: Part 1: This section consists of 232 multiple-choice questions covering various topics such as patient management, history and physical examination, lab and diagnostic studies, diagnosis, prognosis, and pathophysiology. Part 2: The second part features 16 computer-based case simulations, each presenting a patient scenario where candidates must make decisions regarding patient care. Eligibility Criteria To be eligible to sit for the USMLE Step 3 exam, candidates must meet the following criteria: Pass Steps 1 and 2 CK of the USMLE. For international medical graduates (IMGs), their medical school must be listed in the World Directory of Medical Schools (WDOMS) to meet the eligibility requirements set by the Educational Commission for Foreign Medical Graduates (ECFMG). Alternatively, IMGs must possess an equivalent medical degree from a non-American or non-Canadian medical school. Candidates must have completed or be near completion of at least one postgraduate training year in a recognized US graduate medical education (GME) program to fulfill the requirements for a state board license. IMGs must obtain certification from the ECFMG prior to completing Step 3. The application process for Step 3 involves creating an account on the USMLE website, completing the online application, paying the application fee, and submitting documentation of eligibility, including medical school diploma and transcripts. Once approved, candidates can schedule their exam appointment at a Prometric USMLE Step 3 test center located across the United States. For detailed information, candidates can refer to the USMLE Step 3 eligibility requirements and application procedure on the FSMB website: usmle.fsmb.org.